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UConn Health Richard D. Berlin
Center for Cell Analysis & Modeling

Surface Plasmon Resonance

CCAM's Biacore

Concentrations of specific molecular species and kinetic constants for molecular interactions are critical to quantitative knowledge of biological systems. These values can be analyzed in vitro using surface plasmon resonance (SPR) techniques with BIACORE equipment to measure binding of a soluble molecule to its immobilized ligand. These methods allow for high resolution analysis of binding kinetics of molecular interactions. They have been used to study such interactions as RNA-protein, steroid-receptor and substrate- lipid metabolism enzymes.

To use the BiaCore system in your research,please contact Dr. Ann Cowan

 

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